The easiest way to to get to your destination is a direct flight. Direct flights for from Chiang Mai to Mandalay are offered by:
Aviasales.ge suggests buying tickets for Chiang Mai – Mandalay in advance in order to choose the conditions for your flight that best suit your preferences and budget.
Chiang Mai airports serving flights to Mandalay:
Mandalay airports accepting flights from Chiang Mai: